Syble was born September 17, 1932 in Pelzer, South Carolina. Syble grew up in Charlotte, North Carolina with her parents Louis Jackson and Ella (Thomas) Kelly. She graduated from the Harding High School in Charlotte, North Carolina. Syble then received her associate degree in Clerical work, She also received her CNA license. Syble worked for several nursing facilities including Hawthorne Nursing Center in Charlotte, North Carolina and also did private duty nursing until she retired. On April 5, 1962 Syble married Daniel Lee Thrower in South Carolina. The couple made their home in North Carolina before moving to Coffeyville, Kansas in June of 2012.